Mediator of DNA Damage Checkpoint Protein 1 Facilitates V(D)J Recombination in Cells Lacking DNA Repair Factor XLF

DNA double-strand breaks (DSBs) trigger the Ataxia telangiectasia mutated (ATM)-dependent DNA damage response (DDR), which consists of histone H2AX, MDC1, RNF168, 53BP1, PTIP, RIF1, Rev7, and Shieldin. Early stages of B and T lymphocyte development are dependent on recombination activating gene (RAG...

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Detalles Bibliográficos
Autores principales: Beck, Carole, Castañeda-Zegarra, Sergio, Huse, Camilla, Xing, Mengtan, Oksenych, Valentyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023129/
https://www.ncbi.nlm.nih.gov/pubmed/31905950
http://dx.doi.org/10.3390/biom10010060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023129/
https://www.ncbi.nlm.nih.gov/pubmed/31905950
http://dx.doi.org/10.3390/biom10010060

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