Cargando…

Mediator of DNA Damage Checkpoint Protein 1 Facilitates V(D)J Recombination in Cells Lacking DNA Repair Factor XLF

DNA double-strand breaks (DSBs) trigger the Ataxia telangiectasia mutated (ATM)-dependent DNA damage response (DDR), which consists of histone H2AX, MDC1, RNF168, 53BP1, PTIP, RIF1, Rev7, and Shieldin. Early stages of B and T lymphocyte development are dependent on recombination activating gene (RAG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beck, Carole, Castañeda-Zegarra, Sergio, Huse, Camilla, Xing, Mengtan, Oksenych, Valentyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023129/ https://www.ncbi.nlm.nih.gov/pubmed/31905950 http://dx.doi.org/10.3390/biom10010060

Ejemplares similares

Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells
por: Xing, Mengtan, et al.
Publicado: (2019)

Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
por: Gago‐Fuentes, Raquel, et al.
Publicado: (2018)

Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
por: Castañeda-Zegarra, Sergio, et al.
Publicado: (2020)

Non-Homologous End Joining Factors XLF, PAXX and DNA-PKcs Maintain the Neural Stem and Progenitor Cell Population
por: Gago-Fuentes, Raquel, et al.
Publicado: (2020)

ATM Damage Response and XLF Repair Factor are Functionally Redundant In Joining DNA Breaks
por: Zha, Shan, et al.
Publicado: (2010)

Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren
por: Castañeda-Zegarra, Sergio, et al.
Publicado: (2019)

DNA Damage Response
por: Oksenych, Valentyn, et al.
Publicado: (2021)

Cloning, localization and focus formation at DNA damage sites of canine XLF
por: KOIKE, Manabu, et al.
Publicado: (2016)

Robust DNA repair in PAXX‐deficient mammalian cells
por: Dewan, Alisa, et al.
Publicado: (2018)

Feline XLF accumulates at DNA damage sites in a Ku‐dependent manner
por: Koike, Manabu, et al.
Publicado: (2019)

Role of Paralogue of XRCC4 and XLF in DNA Damage Repair and Cancer Development
por: Tang, Jialin, et al.
Publicado: (2022)

DNA Repair and Immune Response: Editorial
por: Oksenych, Valentyn
Publicado: (2022)

Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation
por: KOIKE, Manabu, et al.
Publicado: (2015)

Interaction between Fibroblasts and Immune Cells Following DNA Damage Induced by Ionizing Radiation
por: Ragunathan, Kalaiyarasi, et al.
Publicado: (2020)

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination
por: Lescale, Chloé, et al.
Publicado: (2016)

A human XRCC4–XLF complex bridges DNA
por: Andres, Sara N., et al.
Publicado: (2012)

XLF extends its range from DNA repair to replication
por: Gonzalez-Rodriguez, Yanira, et al.
Publicado: (2019)

Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice
por: Roch, Benoit, et al.
Publicado: (2019)

Two Sides of the Same Coin: TFIIH Complexes in Transcription and DNA Repair
por: Zhovmer, Alexander, et al.
Publicado: (2010)

The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened
por: Cisneros-Aguirre, Metztli, et al.
Publicado: (2022)

Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation
por: McKerlie, Megan, et al.
Publicado: (2013)

Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF
por: Jayaram, Sumithra, et al.
Publicado: (2008)

Corrigendum to: Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells
Publicado: (2020)

XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation
por: Riballo, Enriqueta, et al.
Publicado: (2009)

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
por: Liu, Xiangyu, et al.
Publicado: (2017)

A Single XLF Dimer Bridges DNA Ends During Non-Homologous End Joining
por: Graham, Thomas G.W., et al.
Publicado: (2018)

Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence
por: Gu, Jiafeng, et al.
Publicado: (2007)

RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair
por: Lescale, Chloé, et al.
Publicado: (2016)

The (Lack of) DNA Double-Strand Break Repair Pathway Choice During V(D)J Recombination
por: Libri, Alice, et al.
Publicado: (2022)

The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast
por: Blaikley, Elizabeth J., et al.
Publicado: (2014)

Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes
por: Wang, Hong, et al.
Publicado: (2006)

And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance
por: Chen, Yali, et al.
Publicado: (2017)

Regulation of DNA replication by the S-phase DNA damage checkpoint
por: Willis, Nicholas, et al.
Publicado: (2009)

The Intra-S Checkpoint Responses to DNA Damage
por: Iyer, Divya Ramalingam, et al.
Publicado: (2017)

DNA polymerase delta interacting protein 3 facilitates the activation and maintenance of DNA damage checkpoint in response to replication stress
por: Zhang, Sufang, et al.
Publicado: (2022)

Editorial: Plasticity of immune cells in tumor microenvironment
por: Oksenych, Valentyn
Publicado: (2023)

Direct and Indirect Control of the Initiation of Meiotic Recombination by DNA Damage Checkpoint Mechanisms in Budding Yeast
por: Argunhan, Bilge, et al.
Publicado: (2013)

Increased chromosomal mobility after DNA damage is controlled by interactions between the recombination machinery and the checkpoint
por: Smith, Michael J., et al.
Publicado: (2018)

Cernunnos/XLF Deficiency: A Syndromic Primary Immunodeficiency
por: Çipe, Funda Erol, et al.
Publicado: (2014)

Synthetic lethality between PAXX and XLF in mammalian development
por: Balmus, Gabriel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_mc8fd2c7iiakj7k298o1jsk0kd