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Endoplasmic Reticulum Stress-Induced Resistance to Doxorubicin Is Reversed by Mulberry Leaf Polyphenol Extract in Hepatocellular Carcinoma through Inhibition of COX-2

Mulberry (Morus alba L.) leaves are used in Chinese medicine to treat metabolic disorders. Mulberry leaf polyphenol extracts (MLPE) have recently been shown to exhibit anticancer properties. Endoplasmic reticulum (ER) stress represents a pivotal obstacle in solid tumors, resulting in the antiapoptos...

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Detalles Bibliográficos
Autores principales: Yang, Mon-Yuan, Wu, Cheng-Hsun, Hung, Tung-Wei, Wang, Chau-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023226/
https://www.ncbi.nlm.nih.gov/pubmed/31888113
http://dx.doi.org/10.3390/antiox9010026