Cargando…

Endoplasmic Reticulum Stress-Induced Resistance to Doxorubicin Is Reversed by Mulberry Leaf Polyphenol Extract in Hepatocellular Carcinoma through Inhibition of COX-2

Mulberry (Morus alba L.) leaves are used in Chinese medicine to treat metabolic disorders. Mulberry leaf polyphenol extracts (MLPE) have recently been shown to exhibit anticancer properties. Endoplasmic reticulum (ER) stress represents a pivotal obstacle in solid tumors, resulting in the antiapoptos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Mon-Yuan, Wu, Cheng-Hsun, Hung, Tung-Wei, Wang, Chau-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023226/ https://www.ncbi.nlm.nih.gov/pubmed/31888113 http://dx.doi.org/10.3390/antiox9010026

Ejemplares similares

Mulberry Leaf Polyphenol Extract and Rutin Induces Autophagy Regulated by p53 in Human Hepatoma HepG2 Cells
por: Yu, Meng-Hsun, et al.
Publicado: (2021)

Modulation of endoplasmic reticulum stress and cardiomyocyte apoptosis by mulberry leaf diet in experimental autoimmune myocarditis rats
por: Arumugam, Somasundaram, et al.
Publicado: (2012)

Endoplasmic Reticulum Stress–Induced Resistance to Doxorubicin Is Reversed by Paeonol Treatment in Human Hepatocellular Carcinoma Cells
por: Fan, Lulu, et al.
Publicado: (2013)

Mulberry polyphenol extracts attenuated senescence through inhibition of Ras/ERK via promoting Ras degradation in VSMC
por: Chen, Ching-Pei, et al.
Publicado: (2022)

Mulberry leaf polyphenols alleviated high-fat diet-induced obesity in mice
por: Li, Rui, et al.
Publicado: (2022)

Mulberry leaf extract inhibit hepatocellular carcinoma cell proliferation via depressing IL-6 and TNF-α derived from adipocyte
por: Chang, Chun-Hua, et al.
Publicado: (2018)

Mulberry Leaf and Neochlorogenic Acid Alleviates Glucolipotoxicity-Induced Oxidative Stress and Inhibits Proliferation/Migration via Downregulating Ras and FAK Signaling Pathway in Vascular Smooth Muscle Cell
por: Yang, Tsung-Yuan, et al.
Publicado: (2022)

Mulberry polyphenols ameliorate atherogenic migration and proliferation by degradation of K-Ras and downregulation of its signals in vascular smooth muscle cell
por: Chen, Ching-Pei, et al.
Publicado: (2022)

Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress
por: Peng, Chiung-Huei, et al.
Publicado: (2017)

Inhibitory Effect of Nelumbo nucifera Leaf Extract on 2-Acetylaminofluorene-induced Hepatocarcinogenesis Through Enhancing Antioxidative Potential and Alleviating Inflammation in Rats
por: Yang, Mon-Yuan, et al.
Publicado: (2019)

Natural Polyphenols as SERCA Activators: Role in the Endoplasmic Reticulum Stress-Related Diseases
por: Viskupicova, Jana, et al.
Publicado: (2022)

Mulberry Leaf Polyphenols and Fiber Induce Synergistic Antiobesity and Display a Modulation Effect on Gut Microbiota and Metabolites
por: Li, Qian, et al.
Publicado: (2019)

Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy
por: Malik, Akshi, et al.
Publicado: (2022)

Aqueous Mulberry Leaf Extract Ameliorates Alcoholic Liver Injury Associating with Upregulation of Ethanol Metabolism and Suppression of Hepatic Lipogenesis
por: Lee, Yi-Ju, et al.
Publicado: (2021)

Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress
por: Zhai, Bo, et al.
Publicado: (2015)

Antioxidant and Hemolysis Protective Effects of Polyphenol-Rich Extract from Mulberry Fruits
por: Ajay Krishna, Palanigounder Ganeshan, et al.
Publicado: (2018)

Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
por: Khaled, Jaafar, et al.
Publicado: (2022)

Cardiomyocyte Stim1 Deficiency Exacerbates Doxorubicin Cardiotoxicity by Magnification of Endoplasmic Reticulum Stress
por: Zhu, Jiang, et al.
Publicado: (2021)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

The anti-obesity effect of mulberry leaf (Mori Folium) extracts was increased by bioconversion with Pectinex
por: Han, Joo-Hui, et al.
Publicado: (2022)

Geo-environmental factors and the effectiveness of mulberry leaf extract in managing malaria
por: Pradhan, Sayantan, et al.
Publicado: (2023)

HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress‐driven hepatocellular carcinoma progression
por: He, Lin, et al.
Publicado: (2023)

Endoplasmic Reticulum Stress Promotes iNOS/NO and Influences Inflammation in the Development of Doxorubicin-Induced Cardiomyopathy
por: Bagchi, Ashim K., et al.
Publicado: (2021)

NMDA Receptor Stimulation Induces Reversible Fission of the Neuronal Endoplasmic Reticulum
por: Kucharz, Krzysztof, et al.
Publicado: (2009)

Antidiabetic and Antioxidant Effects and Phytochemicals of Mulberry Fruit (Morus alba L.) Polyphenol Enhanced Extract
por: Wang, Yihai, et al.
Publicado: (2013)

Effects of unaltered and bioconverted mulberry leaf extracts on cellular glucose uptake and antidiabetic action in animals
por: Jung, Sang-Hyuk, et al.
Publicado: (2019)

Mulberry Leaf (Morus alba L.) Extracts and Its Chlorogenic Acid Isomer Component Improve Glucolipotoxicity-Induced Hepatic Lipid Accumulation via Downregulating miR-34a and Decreased Inflammation
por: Yang, Tsung-Yuan, et al.
Publicado: (2022)

Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates
por: Wang, Ruihua, et al.
Publicado: (2018)

Anti-Inflammatory and Anti-Bacterial Potential of Mulberry Leaf Extract on Oral Microorganisms
por: Kim, Dokyeong, et al.
Publicado: (2022)

Antioxidant Effect of Lycium barbarum Leaf through Inflammatory and Endoplasmic Reticulum Stress Mechanism
por: Lee, So Rok, et al.
Publicado: (2020)

Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis
por: Guo, Jun-Jie, et al.
Publicado: (2016)

Resolvin D1 Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Inflammation, Oxidative and Endoplasmic Reticulum Stress
por: Wang, Menglong, et al.
Publicado: (2022)

The involvement of endoplasmic reticulum stress in bile acid-induced hepatocellular injury
por: Adachi, Tetsuo, et al.
Publicado: (2014)

Construction of the endoplasmic reticulum
Publicado: (1989)

Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway
por: Xu, Yuyu, et al.
Publicado: (2018)

A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress
por: Ma, Mengjiao, et al.
Publicado: (2023)

The neuroprotective effects of the combined extract of mulberry fruit and mulberry leaf against hydrogen peroxide-induced cytotoxicity in SH-SY5Y Cells
por: Mairuae, Nootchanat, et al.
Publicado: (2023)

Statistical Design of Sustained-Release Tablet Garcinia cambogia Extract and Bioconverted Mulberry Leaf Extract for Anti-Obesity
por: Lee, Hye-Jin, et al.
Publicado: (2020)

The Effect of Hot-Melt Extrusion of Mulberry Leaf on the Number of Active Compounds and Antioxidant Activity
por: Kim, Hyun-Bok, et al.
Publicado: (2022)

Anti-Inflammatory Activity of Mulberry Leaf Flavonoids In Vitro and In Vivo
por: Lin, Ziwei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ccjanmiblr5a2lsdt41kb1hcfu