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Role of Hfq in Genome Evolution: Instability of G-Quadruplex Sequences in E. coli

Certain G-rich DNA repeats can form quadruplex in bacterial chromatin that can present blocks to DNA replication and, if not properly resolved, may lead to mutations. To understand the participation of quadruplex DNA in genomic instability in Escherichia coli (E. coli), mutation rates were measured...

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Detalles Bibliográficos
Autores principales: Parekh, Virali J., Niccum, Brittany A., Shah, Rachna, Rivera, Marisa A., Novak, Mark J., Geinguenaud, Frederic, Wien, Frank, Arluison, Véronique, Sinden, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023247/
https://www.ncbi.nlm.nih.gov/pubmed/31877879
http://dx.doi.org/10.3390/microorganisms8010028