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Stabilisation and Growth of Metastable Form II of Fluconazole in Amorphous Solid Dispersions

The crystallisation of metastable drug polymorphs in polymer matrices has been reported as a successful approach to enhance the solubility of poorly water-soluble drug molecules. This can be achieved using different polymers, drug to polymer ratios and formulation techniques enabling the formation o...

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Detalles Bibliográficos
Autores principales: Nowak, Maciej, Gajda, Maciej, Baranowski, Przemysław, Szymczyk, Patrycja, Karolewicz, Bożena, Nartowski, Karol P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023302/
https://www.ncbi.nlm.nih.gov/pubmed/31877666
http://dx.doi.org/10.3390/pharmaceutics12010012