4-Aminobenzoic Acid Derivatives: Converting Folate Precursor to Antimicrobial and Cytotoxic Agents

4-aminobenzoic acid (PABA), an essential nutrient for many human pathogens, but dispensable for humans, and its derivatives have exhibited various biological activities. In this study, we combined two pharmacophores using a molecular hybridization approach: this vitamin-like molecule and various aro...

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Detalles Bibliográficos
Autores principales: Krátký, Martin, Konečná, Klára, Janoušek, Jiří, Brablíková, Michaela, Janďourek, Ondřej, Trejtnar, František, Stolaříková, Jiřina, Vinšová, Jarmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023430/
https://www.ncbi.nlm.nih.gov/pubmed/31861596
http://dx.doi.org/10.3390/biom10010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023430/
https://www.ncbi.nlm.nih.gov/pubmed/31861596
http://dx.doi.org/10.3390/biom10010009

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