A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP

The application of in silico modeling to predict the in vivo outcome of an oral drug product is gaining a lot of interest. Fully relying on these models as a surrogate tool requires continuous optimization and validation. To do so, intraluminal and systemic data are desirable to judge the predicted...

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Detalles Bibliográficos
Autores principales: Bermejo, Marival, Hens, Bart, Dickens, Joseph, Mudie, Deanna, Paixão, Paulo, Tsume, Yasuhiro, Shedden, Kerby, Amidon, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023481/
https://www.ncbi.nlm.nih.gov/pubmed/31963448
http://dx.doi.org/10.3390/pharmaceutics12010074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023481/
https://www.ncbi.nlm.nih.gov/pubmed/31963448
http://dx.doi.org/10.3390/pharmaceutics12010074

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