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Mutational signatures: experimental design and analytical framework

Mutational signatures provide a powerful alternative for understanding the pathophysiology of cancer. Currently, experimental efforts aimed at validating and understanding the etiologies of cancer-derived mutational signatures are underway. In this review, we highlight key aspects of mutational sign...

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Detalles Bibliográficos
Autores principales: Koh, Gene, Zou, Xueqing, Nik-Zainal, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023746/
https://www.ncbi.nlm.nih.gov/pubmed/32059681
http://dx.doi.org/10.1186/s13059-020-1951-5