Toll-like receptor 4 deficiency ameliorates β2-microglobulin induced age-related cognition decline due to neuroinflammation in mice

Toll-like receptor 4 (TLR4) is a crucial receptor in neuroinflammation and apoptotic neuronal death, and increasing evidences indicated that β2-microglobulin (B2M) is thought to be a major contributor to age-related cognitive decline. In present study, we designed to investigate the effects of TLR4...

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Detalles Bibliográficos
Autores principales: Zhong, Qi, Zou, Yufeng, Liu, Hongchao, Chen, Ting, Zheng, Feng, Huang, Yifei, Chen, Chang, Zhang, Zongze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023753/
https://www.ncbi.nlm.nih.gov/pubmed/32059688
http://dx.doi.org/10.1186/s13041-020-0559-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023753/
https://www.ncbi.nlm.nih.gov/pubmed/32059688
http://dx.doi.org/10.1186/s13041-020-0559-8

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