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Toll-like receptor 4 deficiency ameliorates β2-microglobulin induced age-related cognition decline due to neuroinflammation in mice

Toll-like receptor 4 (TLR4) is a crucial receptor in neuroinflammation and apoptotic neuronal death, and increasing evidences indicated that β2-microglobulin (B2M) is thought to be a major contributor to age-related cognitive decline. In present study, we designed to investigate the effects of TLR4...

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Detalles Bibliográficos
Autores principales:	Zhong, Qi, Zou, Yufeng, Liu, Hongchao, Chen, Ting, Zheng, Feng, Huang, Yifei, Chen, Chang, Zhang, Zongze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023753/ https://www.ncbi.nlm.nih.gov/pubmed/32059688 http://dx.doi.org/10.1186/s13041-020-0559-8

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