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The modular nature of protein evolution: domain rearrangement rates across eukaryotic life

BACKGROUND: Modularity is important for evolutionary innovation. The recombination of existing units to form larger complexes with new functionalities spares the need to create novel elements from scratch. In proteins, this principle can be observed at the level of protein domains, functional subuni...

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Detalles Bibliográficos
Autores principales: Dohmen, Elias, Klasberg, Steffen, Bornberg-Bauer, Erich, Perrey, Sören, Kemena, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023805/
https://www.ncbi.nlm.nih.gov/pubmed/32059645
http://dx.doi.org/10.1186/s12862-020-1591-0