Secretory clusterin promotes hepatocellular carcinoma progression by facilitating cancer stem cell properties via AKT/GSK-3β/β-catenin axis

BACKGROUND: To explore the modulatory effects and mechanism of secretory clusterin (sCLU) on cancer stem cell (CSC) properties in hepatocellular carcinoma (HCC). METHODS: The effects of sCLU repression or overexpression on chemoresistance, migration, invasion, and tumor growth were detected by MTT,...

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Detalles Bibliográficos
Autores principales: Zheng, Wenjie, Yao, Min, Wu, Mengna, Yang, Junling, Yao, Dengfu, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023808/
https://www.ncbi.nlm.nih.gov/pubmed/32059741
http://dx.doi.org/10.1186/s12967-020-02262-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023808/
https://www.ncbi.nlm.nih.gov/pubmed/32059741
http://dx.doi.org/10.1186/s12967-020-02262-7

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