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Tanshinone IIA prevents platelet activation and down-regulates CD36 and MKK4/JNK2 signaling pathway

BACKGROUND: Tanshinone IIA (TS IIA), a multi-pharmaceutical compound from traditional Chinese herb, is effective for treatment of atherothrombosis. However, the underlying mechanisms of TS IIA-mediated anti-platelet activation effect are still poorly understood. As shown in our previous study, plate...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Zhong, Lin, Mi, Shaohua, Song, Nianpeng, Zhang, Wei, Zhong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023810/
https://www.ncbi.nlm.nih.gov/pubmed/32059638
http://dx.doi.org/10.1186/s12872-019-01289-z