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Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is the second leading cancer killer in the US today and patients with metastatic disease have only a 14% 5-year survival. One of the most impactful recent advances in cancer therapy, immune checkpoint inhibition, has not been shown to be effective for the majority...

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Detalles Bibliográficos
Autores principales: Shen, Yuanyuan, Guan, Yue, Hummel, Justin J., Shyu, Chi-Ren, Mitchem, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023815/
https://www.ncbi.nlm.nih.gov/pubmed/32059711
http://dx.doi.org/10.1186/s12885-020-6513-4