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Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is the second leading cancer killer in the US today and patients with metastatic disease have only a 14% 5-year survival. One of the most impactful recent advances in cancer therapy, immune checkpoint inhibition, has not been shown to be effective for the majority...
Autores principales: | Shen, Yuanyuan, Guan, Yue, Hummel, Justin J., Shyu, Chi-Ren, Mitchem, Jonathan B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023815/ https://www.ncbi.nlm.nih.gov/pubmed/32059711 http://dx.doi.org/10.1186/s12885-020-6513-4 |
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