Transcriptomics Analysis of the Tumor-Inhibitory Pathways of 6-Thioguanine in MCF-7 Cells via Silencing DNMT1 Activity

BACKGROUND: 6-thioguanine (6-TG), as a conventional “ancient” drug for the treatment of acute leukemia, has been proved to have extensive anti-tumor roles. This study was created to investigate the hidden function of 6-TG on the MCF-7 breast cancer cell line (ER+, PR+) and its mechanisms. METHODS: M...

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Detalles Bibliográficos
Autores principales: Li, Hao, An, Xinglan, Zhang, Daoyu, Li, Qi, Zhang, Nan, Yu, Hao, Li, Ziyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023860/
https://www.ncbi.nlm.nih.gov/pubmed/32103989
http://dx.doi.org/10.2147/OTT.S236543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023860/
https://www.ncbi.nlm.nih.gov/pubmed/32103989
http://dx.doi.org/10.2147/OTT.S236543

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