Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathy

The existence of more than 30 strains of transmissible spongiform encephalopathy (TSE) and the paucity of infectivity of purified PrP(Sc), as well as considerations of PrP structure, are inconsistent with the protein-only (prion) theory of TSE. Nucleic acid is a strong contender as a second componen...

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Detalles Bibliográficos
Autores principales: Lathe, Richard, Darlix, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024060/
https://www.ncbi.nlm.nih.gov/pubmed/32025859
http://dx.doi.org/10.1007/s00705-020-04529-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024060/
https://www.ncbi.nlm.nih.gov/pubmed/32025859
http://dx.doi.org/10.1007/s00705-020-04529-2

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