Cargando…

The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

Lung cancer is a leading cause of cancer death worldwide, and non-small-cell lung cancer (NSCLC) accounts for 85% of lung cancer, which is highly metastatic, leading to the poor survival rate of patients. We recently reported that 4-[4-(4-hydroxyphenoxy)phenoxy]phenol (4-HPPP), a phenoxyphenol, exer...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wangta, Wu, Chang-Yi, Lu, Mei-Jei, Chuang, Yung-Jen, Tsai, Eing-Mei, Leu, Steve, Lin, I-Ling, Ko, Chih-Jan, Chiu, Chien-Chih, Chang, Wen-Tsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024103/
https://www.ncbi.nlm.nih.gov/pubmed/32089770
http://dx.doi.org/10.1155/2020/5167292