Design, Synthesis and In Vitro Characterization of Novel Antimicrobial Agents Based on 6-Chloro-9H-carbazol Derivatives and 1,3,4-Oxadiazole Scaffolds

In this paper, we aimed to exploit and combine in the same molecule the carbazole and the 1,3,4-oxadiazole pharmacophores, to obtain novel carprofen derivatives, by using two synthesis pathways. For the first route, the following steps have been followed: (i) (RS)-2-(6-chloro-9H-carbazol-2-yl)propan...

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Detalles Bibliográficos
Autores principales: Bordei Telehoiu, Alexandra T., Nuță, Diana C., Căproiu, Miron T., Dumitrascu, Florea, Zarafu, Irina, Ioniță, Petre, Bădiceanu, Carmellina D., Avram, Speranța, Chifiriuc, Mariana C., Bleotu, Coralia, Limban, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024163/
https://www.ncbi.nlm.nih.gov/pubmed/31936505
http://dx.doi.org/10.3390/molecules25020266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024163/
https://www.ncbi.nlm.nih.gov/pubmed/31936505
http://dx.doi.org/10.3390/molecules25020266

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