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Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives

In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and with a less side-effects, we have designed and synthesized a library of 1,4-disubstituted piperidine derivatives from 4-aminopiperidine derivatives 6. The resulting compound library has been evaluated against c...

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Detalles Bibliográficos
Autores principales: Seck, Rokhyatou, Gassama, Abdoulaye, Cojean, Sandrine, Cavé, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024169/
https://www.ncbi.nlm.nih.gov/pubmed/31940857
http://dx.doi.org/10.3390/molecules25020299