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Dual-Functioning Scaffolds for the Treatment of Spinal Cord Injury: Alginate Nanofibers Loaded with the Sigma 1 Receptor (S1R) Agonist RC-33 in Chitosan Films

The present work proposed a novel therapeutic platform with both neuroprotective and neuroregenerative potential to be used in the treatment of spinal cord injury (SCI). A dual-functioning scaffold for the delivery of the neuroprotective S1R agonist, RC-33, to be locally implanted at the site of SCI...

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Detalles Bibliográficos
Autores principales: Vigani, Barbara, Rossi, Silvia, Sandri, Giuseppina, Bonferoni, Maria Cristina, Rui, Marta, Collina, Simona, Fagiani, Francesca, Lanni, Cristina, Ferrari, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024184/
https://www.ncbi.nlm.nih.gov/pubmed/31887983
http://dx.doi.org/10.3390/md18010021