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A Liposomal Formulation for Improving Solubility and Oral Bioavailability of Nifedipine

Proliposomes were used to improve the solubility and oral bioavailability of nifedipine. Nifedipine proliposomes were prepared by methanol injection-spray drying method. The response surface method was used to optimize formulation to enhance the encapsulation efficiency (EE%) of nifedipine. The part...

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Detalles Bibliográficos
Autores principales: Bi, Ye, Lv, Bingcong, Li, Lianlian, Lee, Robert J., Xie, Jing, Qiu, Zhidong, Teng, Lesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024191/
https://www.ncbi.nlm.nih.gov/pubmed/31947655
http://dx.doi.org/10.3390/molecules25020338