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A Co-Culturing Approach Enables Discovery and Biosynthesis of a Bioactive Indole Alkaloid Metabolite

Whole-genome sequence data of the genus Streptomyces have shown a far greater chemical diversity of metabolites than what have been discovered under typical laboratory fermentation conditions. In our previous natural product discovery efforts on Streptomyces sp. MA37, a bacterium isolated from the r...

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Detalles Bibliográficos
Autores principales: Maglangit, Fleurdeliz, Fang, Qing, Kyeremeh, Kwaku, Sternberg, Jeremy M., Ebel, Rainer, Deng, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024260/
https://www.ncbi.nlm.nih.gov/pubmed/31936318
http://dx.doi.org/10.3390/molecules25020256