Design of Disruptors of the Hsp90–Cdc37 Interface

The molecular chaperone Hsp90 is a ubiquitous ATPase-directed protein responsible for the activation and structural stabilization of a large clientele of proteins. As such, Hsp90 has emerged as a suitable candidate for the treatment of a diverse set of diseases, such as cancer and neurodegeneration....

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Detalles Bibliográficos
Autores principales: D’Annessa, Ilda, Hurwitz, Naama, Pirota, Valentina, Beretta, Giovanni Luca, Tinelli, Stella, Woodford, Mark, Freccero, Mauro, Mollapour, Mehdi, Zaffaroni, Nadia, Wolfson, Haim, Colombo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024268/
https://www.ncbi.nlm.nih.gov/pubmed/31952296
http://dx.doi.org/10.3390/molecules25020360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024268/
https://www.ncbi.nlm.nih.gov/pubmed/31952296
http://dx.doi.org/10.3390/molecules25020360

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