Ubiquitin-Proteasome Modulating Dolabellanes and Secosteroids from Soft Coral Clavularia flava

We performed a high-content screening (HCS) assay aiming to discover bioactive molecules with proteasome inhibitory activity. By structural elucidation, we identified six compounds purified from soft coral Clavularia flava, which potentiates proteasome inhibition. Chemical structure elucidation reve...

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Detalles Bibliográficos
Autores principales: Chiu, Che-Yen, Ling, Xue-Hua, Wang, Shang-Kwei, Duh, Chang-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024272/
https://www.ncbi.nlm.nih.gov/pubmed/31947850
http://dx.doi.org/10.3390/md18010039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024272/
https://www.ncbi.nlm.nih.gov/pubmed/31947850
http://dx.doi.org/10.3390/md18010039

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