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Ubiquitin-Proteasome Modulating Dolabellanes and Secosteroids from Soft Coral Clavularia flava
We performed a high-content screening (HCS) assay aiming to discover bioactive molecules with proteasome inhibitory activity. By structural elucidation, we identified six compounds purified from soft coral Clavularia flava, which potentiates proteasome inhibition. Chemical structure elucidation reve...
Autores principales: | Chiu, Che-Yen, Ling, Xue-Hua, Wang, Shang-Kwei, Duh, Chang-Yih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024272/ https://www.ncbi.nlm.nih.gov/pubmed/31947850 http://dx.doi.org/10.3390/md18010039 |
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