Thymoquinone Enhances Paclitaxel Anti-Breast Cancer Activity via Inhibiting Tumor-Associated Stem Cells Despite Apparent Mathematical Antagonism

Thymoquinone (TQ) has shown substantial evidence for its anticancer effects. Using human breast cancer cells, we evaluated the chemomodulatory effect of TQ on paclitaxel (PTX). TQ showed weak cytotoxic properties against MCF-7 and T47D breast cancer cells with IC(50) values of 64.93 ± 14 µM and 165...

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Detalles Bibliográficos
Autores principales: Bashmail, Hanan A., Alamoudi, Aliaa A., Noorwali, Abdulwahab, Hegazy, Gehan A., Ajabnoor, Ghada M., Al-Abd, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024316/
https://www.ncbi.nlm.nih.gov/pubmed/31968657
http://dx.doi.org/10.3390/molecules25020426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024316/
https://www.ncbi.nlm.nih.gov/pubmed/31968657
http://dx.doi.org/10.3390/molecules25020426

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