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Thymoquinone Enhances Paclitaxel Anti-Breast Cancer Activity via Inhibiting Tumor-Associated Stem Cells Despite Apparent Mathematical Antagonism
Thymoquinone (TQ) has shown substantial evidence for its anticancer effects. Using human breast cancer cells, we evaluated the chemomodulatory effect of TQ on paclitaxel (PTX). TQ showed weak cytotoxic properties against MCF-7 and T47D breast cancer cells with IC(50) values of 64.93 ± 14 µM and 165...
Autores principales: | Bashmail, Hanan A., Alamoudi, Aliaa A., Noorwali, Abdulwahab, Hegazy, Gehan A., Ajabnoor, Ghada M., Al-Abd, Ahmed M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024316/ https://www.ncbi.nlm.nih.gov/pubmed/31968657 http://dx.doi.org/10.3390/molecules25020426 |
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