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Synthetic Approaches to Zetekitoxin AB, a Potent Voltage-Gated Sodium Channel Inhibitor
Voltage-gated sodium channels (Na(V)s) are membrane proteins that are involved in the generation and propagation of action potentials in neurons. Recently, the structure of a complex made of a tetrodotoxin-sensitive (TTX-s) Na(V) subtype with saxitoxin (STX), a shellfish toxin, was determined. STX p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024329/ https://www.ncbi.nlm.nih.gov/pubmed/31888062 http://dx.doi.org/10.3390/md18010024 |