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A New Look into the Mode of Action of Metal-Based Anticancer Drugs

The mode of action of Pt- and Pd-based anticancer agents (cisplatin and Pd(2)Spm) was studied by characterising their impact on DNA. Changes in conformation and mobility at the molecular level in hydrated DNA were analysed by quasi-elastic and inelastic neutron scattering techniques (QENS and INS),...

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Detalles Bibliográficos
Autores principales: Marques, M. Paula M., Batista de Carvalho, Ana L. M., Mamede, Adriana P., Dopplapudi, Asha, Rudić, Svemir, Tyagi, Madhusudan, Garcia Sakai, Victoria, Batista de Carvalho, Luís A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024343/
https://www.ncbi.nlm.nih.gov/pubmed/31936161
http://dx.doi.org/10.3390/molecules25020246