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A New Look into the Mode of Action of Metal-Based Anticancer Drugs
The mode of action of Pt- and Pd-based anticancer agents (cisplatin and Pd(2)Spm) was studied by characterising their impact on DNA. Changes in conformation and mobility at the molecular level in hydrated DNA were analysed by quasi-elastic and inelastic neutron scattering techniques (QENS and INS),...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024343/ https://www.ncbi.nlm.nih.gov/pubmed/31936161 http://dx.doi.org/10.3390/molecules25020246 |