Synthesis of Oligonucleotides Containing 2′-N-alkylaminocarbonyl-2′-amino-LNA (2′-urea-LNA) Moieties Using Post-Synthetic Modification Strategy

The post-synthetic modification of an oligonucleotide is a powerful strategy for the synthesis of various analogs of the oligonucleotide, aiming to achieve the desired functions. In this study, we synthesized the thymidine phosphoramidite of 2′-N-pentafluorophenoxycarbonyl-2′-amino-LNA, which was in...

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Detalles Bibliográficos
Autores principales: Yamashita, Shoko, Nishida, Kodai, Osawa, Takashi, Nakanishi, Ayumi, Ito, Yuta, Hari, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024358/
https://www.ncbi.nlm.nih.gov/pubmed/31952133
http://dx.doi.org/10.3390/molecules25020346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024358/
https://www.ncbi.nlm.nih.gov/pubmed/31952133
http://dx.doi.org/10.3390/molecules25020346

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