Hf(OTf)(4) as a Highly Potent Catalyst for the Synthesis of Mannich Bases under Solvent-Free Conditions

Hf(OTf)(4) was identified as a highly potent catalyst (0.1–0.5 mol%) for three-component Mannich reaction under solvent-free conditions. Hf(OTf)(4)-catalyzed Mannich reaction exhibited excellent regioselectivity and diastereoselectivity when alkyl ketones were employed as substrates. (1)H NMR tracin...

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Detalles Bibliográficos
Autores principales: Han, Shuai-Bo, Wei, Jing-Ying, Peng, Xiao-Chong, Liu, Rong, Gong, Shan-Shan, Sun, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024362/
https://www.ncbi.nlm.nih.gov/pubmed/31963465
http://dx.doi.org/10.3390/molecules25020388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024362/
https://www.ncbi.nlm.nih.gov/pubmed/31963465
http://dx.doi.org/10.3390/molecules25020388

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