One-Pot Multicomponent Synthesis and Cytotoxic Evaluation of Novel 7-Substituted-5-(1H-Indol-3-yl)Tetrazolo[1,5-a] Pyrimidine-6-Carbonitrile

A series of novel 7-substituted-5-(1H-indol-3-yl)tetrazolo[1,5-a]pyrimidine-6-carbonitrile was synthesized via a one-pot, three-multicomponent reaction of appropriate aldehydes, 1H-tetrazole-5-amine and 3-cyanoacetyl indole in catalytic triethylamine. The cytotoxic activity of the new synthesized te...

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Detalles Bibliográficos
Autores principales: Radwan, Mohamed A. A., Alminderej, Fahad M., Awad, Hanem M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024365/
https://www.ncbi.nlm.nih.gov/pubmed/31936309
http://dx.doi.org/10.3390/molecules25020255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024365/
https://www.ncbi.nlm.nih.gov/pubmed/31936309
http://dx.doi.org/10.3390/molecules25020255

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