p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

How ubiquitous transcription factors (TFs) coordinate temporal inputs from broadly expressed epigenetic factors to control cell fate remains poorly understood. Here, we uncover a molecular relationship between p53, an abundant embryonic TF, and WDR5, an essential member of the MLL chromatin modifyin...

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Detalles Bibliográficos
Autores principales: Li, Qiang, Mao, Fengbiao, Zhou, Bo, Huang, Yuanhao, Zou, Zhenhua, denDekker, Aaron D., Xu, Jing, Hou, Sean, Liu, Jie, Dou, Yali, Rao, Rajesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024586/
https://www.ncbi.nlm.nih.gov/pubmed/31940490
http://dx.doi.org/10.1016/j.celrep.2019.12.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024586/
https://www.ncbi.nlm.nih.gov/pubmed/31940490
http://dx.doi.org/10.1016/j.celrep.2019.12.039

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