Cargando…

p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

How ubiquitous transcription factors (TFs) coordinate temporal inputs from broadly expressed epigenetic factors to control cell fate remains poorly understood. Here, we uncover a molecular relationship between p53, an abundant embryonic TF, and WDR5, an essential member of the MLL chromatin modifyin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qiang, Mao, Fengbiao, Zhou, Bo, Huang, Yuanhao, Zou, Zhenhua, denDekker, Aaron D., Xu, Jing, Hou, Sean, Liu, Jie, Dou, Yali, Rao, Rajesh C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024586/ https://www.ncbi.nlm.nih.gov/pubmed/31940490 http://dx.doi.org/10.1016/j.celrep.2019.12.039

Ejemplares similares

p53 inactivation unmasks histone methylation-independent WDR5 functions that drive self-renewal and differentiation of pluripotent stem cells
por: Li, Qiang, et al.
Publicado: (2021)

Knockdown of IKK1/2 Promotes Differentiation of Mouse Embryonic Stem Cells into Neuroectoderm at the Expense of Mesoderm
por: Lüningschrör, Patrick, et al.
Publicado: (2012)

A p38mapk-p53 cascade regulates mesodermal differentiation and neurogenesis of embryonic stem cells
por: Hadjal, Y, et al.
Publicado: (2013)

Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo
por: Saykali, Bechara, et al.
Publicado: (2019)

Tissue Reactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Tumors of Neuroectodermal, Mesodermal, and Epithelial Origin
por: Blanco, Rancés, et al.
Publicado: (2013)

Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro
por: Wang, Tao, et al.
Publicado: (2010)

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias
por: Calero-Nieto, F J, et al.
Publicado: (2013)

Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation
por: Sarrach, Sannia, et al.
Publicado: (2018)

Arid3a regulates mesoderm differentiation in mouse embryonic stem cells
por: Popowski, Melissa, et al.
Publicado: (2017)

From Bipotent Neuromesodermal Progenitors to Neural-Mesodermal Interactions during Embryonic Development
por: Kahane, Nitza, et al.
Publicado: (2021)

Highly parallelized human embryonic stem cell differentiation to cardiac mesoderm in nanoliter chambers on a microfluidic chip
por: Vollertsen, Anke R., et al.
Publicado: (2021)

A dual role of the extracellular domain of Drosophila Crumbs for morphogenesis of the embryonic neuroectoderm
por: Das, Shradha, et al.
Publicado: (2018)

Utx Is Required for Proper Induction of Ectoderm and Mesoderm during Differentiation of Embryonic Stem Cells
por: Morales Torres, Cristina, et al.
Publicado: (2013)

Mesodermal gene expression during the embryonic and larval development of the articulate brachiopod Terebratalia transversa
por: Passamaneck, Yale J, et al.
Publicado: (2015)

MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program
por: Xu, Jing, et al.
Publicado: (2016)

The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system
por: Burns, A S Y W, et al.
Publicado: (2002)

Dysregulation of intercellular signaling by MOF deletion leads to liver injury
por: Lei, Hongwei, et al.
Publicado: (2021)

Efficient Differentiation of Embryonic Stem Cells into Mesodermal Precursors by BMP, Retinoic Acid and Notch Signalling
por: Torres, Josema, et al.
Publicado: (2012)

Histone Deacetylase 1 and 3 Regulate the Mesodermal Lineage Commitment of Mouse Embryonic Stem Cells
por: Lv, Weiying, et al.
Publicado: (2014)

Dual specificity phosphatase 7 drives the formation of cardiac mesoderm in mouse embryonic stem cells
por: Sladeček, Stanislava, et al.
Publicado: (2022)

CTCF acetylation at lysine 20 is required for the early cardiac mesoderm differentiation of embryonic stem cells
por: Gong, Shixin, et al.
Publicado: (2022)

The lateral plate mesoderm
por: Prummel, Karin D., et al.
Publicado: (2020)

Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses
por: Inoue, Daigo, et al.
Publicado: (2017)

An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5
por: Ee, Ly-Sha, et al.
Publicado: (2017)

Structural insights into the activation of USP46 by WDR48 and WDR20
por: Zhu, Hanwen, et al.
Publicado: (2019)

TET1 Deficiency Impairs Morphogen-free Differentiation of Human Embryonic Stem Cells to Neuroectoderm
por: Li, Hanqin, et al.
Publicado: (2020)

Hhex and Cer1 Mediate the Sox17 Pathway for Cardiac Mesoderm Formation in Embryonic Stem Cells
por: Liu, Yu, et al.
Publicado: (2014)

CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells
por: Kotoku, Tomomi, et al.
Publicado: (2016)

Prostaglandin E(2) Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells
por: Zhang, Bowen, et al.
Publicado: (2018)

Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1
por: Wesely, Josephine, et al.
Publicado: (2017)

Integrating single-cell transcriptomes, chromatin accessibility, and multiomics analysis of mesoderm-induced embryonic stem cells
por: Ko, Kyung Dae, et al.
Publicado: (2023)

Population-level antagonism between FGF and BMP signaling steers mesoderm differentiation in embryonic stem cells
por: Gattiglio, Marina, et al.
Publicado: (2023)

Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
por: Ayad, Nadia M.E., et al.
Publicado: (2023)

Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm
por: Wang, Huijia, et al.
Publicado: (2019)

WDR72 regulates vesicle trafficking in ameloblasts
por: Katsura, Kaitlin, et al.
Publicado: (2022)

High grade sarcoma, with predominant neuroectodermal and minor embryonal rhabdomyosarcomatous tumor of the uterus: A case report
por: Chang, Leona, et al.
Publicado: (2019)

A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis
por: Paik, Elizabeth J., et al.
Publicado: (2013)

Contribution of Distinct Homeodomain DNA Binding Specificities to Drosophila Embryonic Mesodermal Cell-Specific Gene Expression Programs
por: Busser, Brian W., et al.
Publicado: (2013)

Establishment of A Protocol for In Vitro Culture of Cardiogenic Mesodermal Cells Derived from Human Embryonic Stem Cells
por: Vahdat, Sadaf, et al.
Publicado: (2019)

Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination
por: Guo, Hanqing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_90b5q7ic6tlun5fp5ikvv4j2ra