A new mechanism for cannabidiol in regulating the one‐carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models

BACKGROUND AND PURPOSE: Epidiolex™, a form of highly purified cannabidiol (CBD) derived from Cannabis plants, has demonstrated seizure control activity in patients with Dravet syndrome, without a fully elucidated mechanism of action. We have employed an unbiased approach to investigate this mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Perry, Christopher J., Finch, Paul, Müller‐Taubenberger, Annette, Leung, Kit‐Yi, Warren, Eleanor C., Damstra‐Oddy, Joseph, Sharma, Devdutt, Patra, Pabitra H., Glyn, Sarah, Boberska, Joanna, Stewart, Balint, Baldwin, Amy, Piscitelli, Fabiana, Harvey, Robert J., Harwood, Adrian, Thompson, Christopher, Claus, Sandrine P., Greene, Nicholas D.E., McNeish, Alister J., Williams, Claire M., Whalley, Benjamin J., Williams, Robin S.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024701/
https://www.ncbi.nlm.nih.gov/pubmed/31693171
http://dx.doi.org/10.1111/bph.14892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024701/
https://www.ncbi.nlm.nih.gov/pubmed/31693171
http://dx.doi.org/10.1111/bph.14892

Ejemplares similares