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Antithrombotic effect of SP‐8008, a benzoic acid derivative, through the selective inhibition of shear stress‐induced platelet aggregation

BACKGROUND AND PURPOSE: Bleeding is one of the most critical adverse effects of antithrombotic drugs, and many efforts have been made to discover novel antiplatelet agents without bleeding complications. Shear stress‐induced platelet aggregation (SIPA), where the interaction of von Willebrand factor...

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Detalles Bibliográficos
Autores principales: Ngo, Thien, Kim, Keunyoung, Bian, Yiying, Nam, Gibeom, Park, Hyun‐Ju, Lee, Kiho, Cho, Geum‐Sil, Ryu, Jei‐Man, Lim, Kyung‐Min, Chung, Jin‐Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024737/
https://www.ncbi.nlm.nih.gov/pubmed/31648364
http://dx.doi.org/10.1111/bph.14894