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Efflux Pumps Contribute to Intrinsic Clarithromycin Resistance in Clinical, Mycobacterium abscessus Isolates

PURPOSE: The emergence of clarithromycin resistance is a challenge in treating Mycobacterium abscessus infections. Known mechanisms that contribute to intrinsic clarithromycin resistance focus on rrl gene-related mutations, but resistant clinical isolates often exhibit an inconsistent rrl genotype....

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Detalles Bibliográficos
Autores principales: Guo, Qi, Chen, Jianhui, Zhang, Shaoyan, Zou, Yuzhen, Zhang, Yongjie, Huang, Dongdong, Zhang, Zhemin, Li, Bing, Chu, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024787/
https://www.ncbi.nlm.nih.gov/pubmed/32104016
http://dx.doi.org/10.2147/IDR.S239850