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Design of a Novel Theranostic Nanomedicine (III): Synthesis and Physicochemical Properties of Tumor-Targeting Cisplatin Conjugated to a Hydrophilic Polyphosphazene

PURPOSE: A new theranostic nanomedicine involving anticancer-active cisplatin moiety was designed to study its tumor-targeting properties as well as its drug efficacy and toxicity. METHODS: A cisplatin carrier polymer was prepared by grafting equimolar polyethylene glycol of a molecular weight of 55...

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Detalles Bibliográficos
Autores principales: Patil, Basavaraj R, Kang, Su Yeon, Jung, Da Hee, Avaji, Prakash G, Jun, Yong Joo, Lee, Hwa Jeong, Sohn, Youn Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024790/
https://www.ncbi.nlm.nih.gov/pubmed/32103951
http://dx.doi.org/10.2147/IJN.S235618