γ-Catenin Overexpression in AML Patients May Promote Tumor Cell Survival via Activation of the Wnt/β-Catenin Axis

BACKGROUND: Canonical Wnt/β-catenin signaling is frequently dysregulated in acute myeloid leukemia (AML) and has been implicated in leukemogenesis. γ-catenin was previously demonstrated to be associated with the nuclear localization of β-catenin, the central mediator, and to exert oncogenic effects...

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Detalles Bibliográficos
Autores principales: Qian, Jiejin, Huang, Xianbo, Zhang, Yinyin, Ye, Xiujin, Qian, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024797/
https://www.ncbi.nlm.nih.gov/pubmed/32103994
http://dx.doi.org/10.2147/OTT.S230873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024797/
https://www.ncbi.nlm.nih.gov/pubmed/32103994
http://dx.doi.org/10.2147/OTT.S230873

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