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Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly

BACKGROUND: The bacterial cell envelope is comprised of the cell membrane and the cell wall. The bacterial cell wall provides rigidity to the cell and protects the organism from potential harmful substances also. Cell wall biosynthesis is an important physiological process for bacterial survival and...

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Detalles Bibliográficos
Autores principales: Chauhan, Jay, Yu, Wenbo, Cardinale, Steven, Opperman, Timothy J, MacKerell, Alexander D, Fletcher, Steven, de Leeuw, Erik PH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024799/
https://www.ncbi.nlm.nih.gov/pubmed/32103898
http://dx.doi.org/10.2147/DDDT.S226313