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Effect of puerarin on action potential and sodium channel activation in human hypertrophic cardiomyocytes

Objective: To study the effect of puerarin on electrophysiology using a hypertrophic cardiomyocyte (HC) model. Materials and methods: Human urine epithelial cells were used to generate the HC model (hiPSC-CM). Cardiomyocyte hypertrophy was induced by applying 10 nM endothelin-1 (ET-1). Effects of pu...

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Detalles Bibliográficos
Autores principales: Lin, Yu-hui, Ni, Xiao-Bin, Zhang, Jian-wu, Ou, Cai-wen, He, Xiao-qing, Dai, Wen-jun, Chen, Xi-ming, Chen, Min-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024842/
https://www.ncbi.nlm.nih.gov/pubmed/32003781
http://dx.doi.org/10.1042/BSR20193369