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Long Noncoding RNA X-Inactive Specific Transcript Facilitates Cellular Functions in Melanoma via miR-139-5p/ROCK1 Pathway

PURPOSE: Although X-inactive specific transcript (XIST) is known to play a critical role in the pathogenesis of melanoma, the mechanisms through which this remains unclear. METHODS: RNAseq, immunohistochemistry, and qRT-PCR were used to identify the levels of XIST, miR-139-5p, and Rho-Associated Coi...

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Detalles Bibliográficos
Autores principales: Tian, Ke, Sun, Dongxia, Chen, Min, Yang, Yifei, Wang, Fang, Guo, Taotao, Shi, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024886/
https://www.ncbi.nlm.nih.gov/pubmed/32103995
http://dx.doi.org/10.2147/OTT.S225661