Cargando…

Long Noncoding RNA X-Inactive Specific Transcript Facilitates Cellular Functions in Melanoma via miR-139-5p/ROCK1 Pathway

PURPOSE: Although X-inactive specific transcript (XIST) is known to play a critical role in the pathogenesis of melanoma, the mechanisms through which this remains unclear. METHODS: RNAseq, immunohistochemistry, and qRT-PCR were used to identify the levels of XIST, miR-139-5p, and Rho-Associated Coi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Ke, Sun, Dongxia, Chen, Min, Yang, Yifei, Wang, Fang, Guo, Taotao, Shi, Zhimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024886/ https://www.ncbi.nlm.nih.gov/pubmed/32103995 http://dx.doi.org/10.2147/OTT.S225661

Ejemplares similares

Long Noncoding RNA X-Inactive Specific Transcript Facilitates Cellular Functions in Melanoma via miR-139-5p/ROCK1 Pathway [Retraction]
Publicado: (2021)

Regulation of Oncogenic Targets by the Tumor-Suppressive miR-139 Duplex (miR-139-5p and miR-139-3p) in Renal Cell Carcinoma
por: Okada, Reona, et al.
Publicado: (2020)

Long noncoding RNA X-inactive specific transcript as a prognostic factor in cancer patients: A meta-analysis based on retrospective studies
por: Chen, Jinbo, et al.
Publicado: (2019)

X-Inactive-Specific Transcript: Review of Its Functions in the Carcinogenesis
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

Positioning X for inactivity
por: Williams, Ruth
Publicado: (2007)

Upregulation of tissue long noncoding RNA X inactive specific transcript predicts poor postoperative survival in patients with non-small cell lung cancer
por: Fang, Hengxiao, et al.
Publicado: (2020)

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer
por: Chaligné, Ronan, et al.
Publicado: (2015)

Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathy
por: Xu, Jia, et al.
Publicado: (2022)

Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation
por: Bauer, Moritz, et al.
Publicado: (2021)

Long noncoding RNA just proximal to X‐inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A‐dependent manner in glioblastoma multiforme cells
por: Li, Xu Dong, et al.
Publicado: (2021)

Abstract 139: Prognostic Factors In Determining The Recurrence Of Desmoplastic Melanoma
por: Persing, Sarah, et al.
Publicado: (2019)

5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway
por: Tonon, Federica, et al.
Publicado: (2022)

Long noncoding RNA Gomafu upregulates Foxo1 expression to promote hepatic insulin resistance by sponging miR-139-5p
por: Yan, Caifeng, et al.
Publicado: (2018)

Long Noncoding RNA X-Inactive Specific Transcript (XIST) Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells by Sponging MicroRNA-214-3p
por: Feng, Yimiao, et al.
Publicado: (2020)

Long noncoding RNA X‐inactive specific transcript (lncRNA XIST) inhibits hepatic insulin resistance by competitively binding microRNA‐182‐5p
por: Zhong, Guoqing, et al.
Publicado: (2023)

Baicalein Induces Apoptosis of Pancreatic Cancer Cells by Regulating the Expression of miR-139-3p and miR-196b-5p
por: Ma, Danhui, et al.
Publicado: (2021)

Dual tumor‐suppressors miR‐139‐5p and miR‐139‐3p targeting matrix metalloprotease 11 in bladder cancer
por: Yonemori, Masaya, et al.
Publicado: (2016)

Circ_0000064 promotes high glucose-induced renal tubular epithelial cells injury to facilitate diabetic nephropathy progression through miR-532-3p/ROCK1 axis
por: Wang, Huanlan, et al.
Publicado: (2022)

Random replication of the inactive X chromosome
por: Koren, Amnon, et al.
Publicado: (2014)

Structural aspects of the inactive X chromosome
por: Bonora, Giancarlo, et al.
Publicado: (2017)

The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory
por: Ridings-Figueroa, Rebeca, et al.
Publicado: (2017)

Spatial organization of active and inactive genes and noncoding DNA within chromosome territories
por: Mahy, Nicola L., et al.
Publicado: (2002)

Long Noncoding RNA X-Inactive-Specific Transcript Promotes the Secretion of Inflammatory Cytokines in LPS Stimulated Astrocyte Cell Via Sponging miR-29c-3p and Regulating Nuclear Factor of Activated T cell 5 Expression
por: Zhang, Mengqi, et al.
Publicado: (2021)

Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma
por: Koma, Ayaka, et al.
Publicado: (2021)

MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM
por: Wang, Yixuan, et al.
Publicado: (2018)

Perturbed maintenance of transcriptional repression on the inactive X-chromosome in the mouse brain after Xist deletion
por: Adrianse, Robin L., et al.
Publicado: (2018)

Silencing of long noncoding RNA X-inactive specific transcript alleviates Aβ1-42-induced microglia-mediated neurotoxicity by shifting microglial M1/M2 polarization
por: Zhao, Kun-Peng, et al.
Publicado: (2023)

Reactivation of the inactive X chromosome in development and reprogramming
por: Ohhata, Tatsuya, et al.
Publicado: (2012)

Bipartite structure of the inactive mouse X chromosome
por: Deng, Xinxian, et al.
Publicado: (2015)

Downregulation of lncRNA X Inactive Specific Transcript (XIST) Suppresses Cell Proliferation and Enhances Radiosensitivity by Upregulating mir-29c in Nasopharyngeal Carcinoma Cells
por: Han, Qian, et al.
Publicado: (2017)

Limited Evidence for Protein Products of Noncoding Transcripts in the HEK293T Cellular Cytosol
por: Bogaert, Annelies, et al.
Publicado: (2022)

The human inactive X chromosome modulates expression of the active X chromosome
por: San Roman, Adrianna K., et al.
Publicado: (2023)

Cucurbitacin B Inhibits Cell Proliferation by Regulating X-Inactive Specific Transcript Expression in Tongue Cancer
por: Tao, Boqiang, et al.
Publicado: (2021)

Silencing long noncoding RNA NEAT1 alleviates acute liver failure via the EZH2-mediated microRNA-139/PUMA axis
por: Wang, Qiang, et al.
Publicado: (2021)

Tumor-suppressor role of miR-139-5p in endometrial cancer
por: Liu, JinHui, et al.
Publicado: (2018)

The role of miR-139-5p in radioiodine-resistant thyroid cancer
por: Pecce, V., et al.
Publicado: (2023)

Long Noncoding RNA HAGLROS Promotes Cell Invasion and Metastasis by Sponging miR-152 and Upregulating ROCK1 Expression in Osteosarcoma
por: Zhou, Kaifeng, et al.
Publicado: (2020)

miR-139-5p and miR-451a as a Diagnostic Biomarker in LUSC
por: Gao, Bo, et al.
Publicado: (2023)

Upregulation of Long Noncoding RNA (lncRNA) X-Inactive Specific Transcript (XIST) is Associated with Cisplatin Resistance in Non-Small Cell Lung Cancer (NSCLC) by Downregulating MicroRNA-144-3p
por: Tian, Lin-Juan, et al.
Publicado: (2019)

LncRNA CTBP1-AS2 Facilitates Gastric Cancer Progression via Regulating the miR-139-3p/MMP11 Axis
por: Yang, Yudan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lurr39gpi3ij39pb38lnjsqn29