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Implications of Oxidative Stress and Cellular Senescence in Age-Related Thymus Involution
The human thymus is a primary lymphoepithelial organ which supports the production of self-tolerant T cells with competent and regulatory functions. Paradoxically, despite the crucial role that it exerts in T cell-mediated immunity and prevention of systemic autoimmunity, the thymus is the first org...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025075/ https://www.ncbi.nlm.nih.gov/pubmed/32089780 http://dx.doi.org/10.1155/2020/7986071 |