Implications of Oxidative Stress and Cellular Senescence in Age-Related Thymus Involution

The human thymus is a primary lymphoepithelial organ which supports the production of self-tolerant T cells with competent and regulatory functions. Paradoxically, despite the crucial role that it exerts in T cell-mediated immunity and prevention of systemic autoimmunity, the thymus is the first org...

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Detalles Bibliográficos
Autores principales: Barbouti, Alexandra, Vasileiou, Panagiotis V. S., Evangelou, Konstantinos, Vlasis, Konstantinos G., Papoudou-Bai, Alexandra, Gorgoulis, Vassilis G., Kanavaros, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025075/
https://www.ncbi.nlm.nih.gov/pubmed/32089780
http://dx.doi.org/10.1155/2020/7986071

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