Systematic genetics and single‐cell imaging reveal widespread morphological pleiotropy and cell‐to‐cell variability

Our ability to understand the genotype‐to‐phenotype relationship is hindered by the lack of detailed understanding of phenotypes at a single‐cell level. To systematically assess cell‐to‐cell phenotypic variability, we combined automated yeast genetics, high‐content screening and neural network‐based...

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Detalles Bibliográficos
Autores principales: Mattiazzi Usaj, Mojca, Sahin, Nil, Friesen, Helena, Pons, Carles, Usaj, Matej, Masinas, Myra Paz D, Shuteriqi, Ermira, Shkurin, Aleksei, Aloy, Patrick, Morris, Quaid, Boone, Charles, Andrews, Brenda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025093/
https://www.ncbi.nlm.nih.gov/pubmed/32064787
http://dx.doi.org/10.15252/msb.20199243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025093/
https://www.ncbi.nlm.nih.gov/pubmed/32064787
http://dx.doi.org/10.15252/msb.20199243

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