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Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2

In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs) and synaptonemal complexes. Here, we show tha...

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Detalles Bibliográficos
Autores principales: McNicoll, François, Kühnel, Anne, Biswas, Uddipta, Hempel, Kai, Whelan, Gabriela, Eichele, Gregor, Jessberger, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025286/
https://www.ncbi.nlm.nih.gov/pubmed/32051254
http://dx.doi.org/10.26508/lsa.201900564