Na(+)/K(+)-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes

Compromised Na(+)/K(+)-ATPase function is associated with the occurrence of spreading depolarization (SD). Mutations in ATP1A2, the gene encoding the α2 isoform of the Na(+)/K(+)-ATPase, were identified in patients with familial hemiplegic migraine type 2 (FHM2), a Mendelian model disease for SD. Th...

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Detalles Bibliográficos
Autores principales: Reiffurth, Clemens, Alam, Mesbah, Zahedi-Khorasani, Mahdi, Major, Sebastian, Dreier, Jens P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025397/
https://www.ncbi.nlm.nih.gov/pubmed/30819023
http://dx.doi.org/10.1177/0271678X19833757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025397/
https://www.ncbi.nlm.nih.gov/pubmed/30819023
http://dx.doi.org/10.1177/0271678X19833757

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